Announcements
- Meyer Shank Racing announced that Helio Castroneves will drive the No. 06 Honda full-time next season.
- Juncos Hollinger Racing announced that Callum Ilott will drive the No. 77 Chevrolet full-time next season.
- Andretti Autosport announced that Romain Grosjean will drive the No. 28 Honda full-time next season.
- Ed Carpenter Racing announced that Rinus VeeKay will return to drive the No. 21 Chevrolet next season.
- Meyer Shank Racing announced that Simon Pagenaud will drive the No. 60 Honda next season.
- Rahal Letterman Lanigan Racing announced that Jack Harvey will drive the No. 45 Honda next season.
- Rahal Letterman Lanigan Racing announced that Christian Lundgaard will drive the No. 30 Honda next season.
- Andretti Autosport announced that Devlin DeFrancesco will drive the No. 29 Honda next season.
- AJ Foyt Racing announced that Kyle Kirkwood will drive the No. 14 Chevrolet next season.
- AJ Foyt Racing announced that Dalton Kellett will return to drive the No. 4 Chevrolet next season.
- Dale Coyne w/ Rick Ware Racing announced that Takuma Sato will drive the No. 51 Honda next season.
- Dreyer & Reinbold Racing announced that Sage Karam and Santino Ferrucci will drive for the team in the Indianapolis 500.
- Chip Ganassi Racing announced that Jimmie Johnson will run the full 2022 season in the No. 48 Honda.
- Dale Coyne w/ HMD Motorsports announced that David Malukas will drive the No. 18 Honda next season.
- Arrow McLaren SP announced that Juan Montoya will drive the No. 6 Chevrolet for the team in the Indianapolis 500.
- Ed Carpenter Racing announced that Conor Daly will return to drive the No. 20 Chevrolet full-time next season.
- AJ Foyt Racing announced that Tatiana Calderon will drive the No. 11 Chevrolet on road and street course races.
- Chip Ganassi Racing announced that Tony Kanaan will be back in a fifth car for the Indianapolis 500.
Rumors and Speculation
- Carlin Racing could potentially merge/partner with Juncos Hollinger Racing. Max Chilton’s status remains up in the air.
- Ed Carpenter will drive a third car in the Indianapolis 500 and possibly other oval races later in the season.
- Arrow McLaren SP is interested in running a third entry at select races this season.
